Adverse effects of paternal obesity on the motile spermatozoa quality

Georges Raad, Joseph Azouri , Kamal Rizk , Nina S. Zeidan, Jessica Azouri , Valerie Grandjean, Mira Hazzour

Online 2019 February 11th,


Growing evidence suggests that paternal obesity may decrease male fertility potential. During infertility treatment with intra-cytoplasmic sperm injection (ICSI), a morphologically normal motile spermatozoon is injected into a mature egg, when possible. However, sperm motility and morphology per se do not reflect the sperm molecular composition. In this study, we aimed to assess the quality of motile spermatozoa in the context of obesity by analysing their conventional and molecular characteristics as well as their ability to promote early embryonic development.

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